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Contraindicated (one)pentobarbital will decrease the level or influence of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with strong CYP3A4 inducers is not advisablepentobarbital will lower the extent or outcome of armodafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolis